Leukocyte Adhesion to Endothelium

  • Martin H. Thornhill
  • Dorian O. Haskard
Part of the Blood Cell Biochemistry book series (BLBI, volume 5)


The recruitment of leukocytes from the blood is a prerequisite for their participation in inflammatory responses within the tissues. In the case of monocytes, a low level of emigration takes place under physiological conditions, but this is greatly increased in the inflammatory setting. An analysis of mechanisms of monocyte—endothelial cell (EC) adhesion is therefore of great relevance to understanding the pathophysiology of diverse acute and chronic inflammatory conditions as well as that of wound healing and tissue repair.


Human Endothelial Cell Leukocyte Adhesion Monocyte Migration Leukocyte Adhesion Molecule Leukocyte Adhesion Deficiency 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Martin H. Thornhill
    • 1
  • Dorian O. Haskard
    • 2
  1. 1.Department of Oral Medicine and PeriodontologyThe London Hospital Medical CollegeLondonUK
  2. 2.Rheumatology Unit, Department of Medicine, Royal Postgraduate Medical SchoolHammersmith HospitalLondonUK

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