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Novel Antiinfective Biomaterials by Polymer Modification

  • W. Kohnen
  • B. Jansen
  • D. Ruiten
  • H. Steinhauser
  • G. Pulverer

Abstract

The first significant step in the pathogenesis of polymer-associated infections (foreign-body infections) is the adhesion of bacteria to the synthetic material. The development of an anti-adhesive synthetic material seems to be a promising method to prevent that kind of infection. A possible approach is to modify the polymer surface without affecting the bulk properties (e.g. mechanical stability, elasticity). An elegant and versatile method to achieve this is the glow discharge technique (NT-plasma), where the surface of a synthetic material is exposed to a glow discharge under reduced pressure.

Keywords

Acrylic Acid Glow Discharge Polymer Surface Synthetic Material Bacterial Adhesion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • W. Kohnen
    • 1
    • 2
  • B. Jansen
    • 1
    • 2
  • D. Ruiten
    • 1
    • 2
  • H. Steinhauser
    • 1
    • 2
  • G. Pulverer
    • 1
    • 2
  1. 1.Institute of Medical Microbiology and HygieneUniversity of CologneCologne 41Germany
  2. 2.Institute of Physical ChemistryUniversity of CologneCologne 41Germany

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