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The Possible Roles of Astrocytes in Energy Metabolism of the Brain

  • Bernd Hamprecht
  • Ralf Dringen
  • Brigitte Pfeiffer
  • Georg Kurz
Part of the Altschul Symposia Series book series (ALSS, volume 2)

Abstract

In the brain astrocytes are situated in a key position between the microvessels and the other cell types, neurons and oligodendrocytes. If one considers the narrow extracellular space between the brain cells, the conclusion appears inescapable that the nutrients of the brain, such as the quantitatively most important substrates for the generation of energy, glucose and oxygen, must cross the astrocytes to reach their metabolic destination in the neurons and oligodendrocytes. This location also could be the prerequisite for playing a pivotal role in controlling energy metabolism of the brain. However, in saying this one has to add immediately that little is known on such an -anthropomorphically seen — attractive function of astrocytes.

Keywords

Glial Fibrillary Acidic Protein Malic Enzyme Glycogen Phosphorylase Astroglial Cell Glucosyl Residue 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Bernd Hamprecht
    • 1
  • Ralf Dringen
    • 1
  • Brigitte Pfeiffer
    • 1
  • Georg Kurz
    • 1
  1. 1.Physiologisch-Chemisches Institut der UniversitätUniversität TübingenTübingenGermany

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