Biomechanics of Blood Cells: A Historical Perspective

  • Richard Skalak


The notion that all animals and plants are made up of individual living cells and their products is a relatively new concept, dating back to approximately 150 years ago. The application of continuum mechanics to the passive and active behaviors of cells is even much more recent. Detailed analytical and computational solutions describing the deformation of cells and their components has only been carried through extensively in the last two or three decades. In the present paper, the historical development of ideas concerning the cellular nature of all living matter will be outlined first. Secondly, the development of analyses of blood flow will be sketched and thirdly, the application of continuum mechanics to individual blood cells and their component parts will be outlined.


Capillary Flow Capillary Blood Flow Cell Theory Serous Layer Germinal Membrane 


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Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Richard Skalak
    • 1
  1. 1.Department of BioengineeringUniversity of California, San DiegoLa JollaUSA

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