Abstract
Vinblastine and vincristine (Fig. 1) are naturally occurring vinca alkaloids present in the Madagascar Periwinkle plant. Vindesine is a semi-synthetic vinca alkaloid, derived from vinblastine. The vinca alkaloids are active against various types of cancer, e.g. Hodgkin’s disease, lymphomas and testicular carcinoma [1].
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Creasey, W.A. (1981) in Cancer and Chemotherapy, Vol. 3 (Crooke, S.T. & Prestayko, A.W., eds.), Academic Press, N.York, pp. 79–91.
Sethi, V.S. & Kimball, J.C. (1981) Cancer Chemother. Pharmacol. 6, 111–115.
Van den Berg, H.W., Desai, Z.R., Wilson, R., Kennedy, G., Bridges, J.M. & Shanks, R.G. (1982) Cancer Chemother. Pharmacol. 8, 215–219.
Fuks, J.W., Egorin, M.J., Aisner, J., Van Echo, D.A., Ostrow, S., Bachur, N.R. & Wiernik, P.H. (1983) Cancer Chemother. Pharmacol. 10, 104–108.
Vendrig, D.E.M.M., Teeuwsen, J. & Holthuis, J.J.M. (1988) J. Chromatog. 424, 83–94.
Vendrig, D.E.M.M., Holthuis, J.J.M., Erdélyi-Toth, V. & Kulshoff, A. (1987) J. Chromatog. 414, 91–100.
Vendrig, D.E.M.M., Smeets, B.P.G.M., Beijnen, J.H., van der Houwen, O.A.J.G. & Holthuis, J.J.M. (1988) Int. J. Pharm. 43, in press.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1988 Springer Science+Business Media New York
About this chapter
Cite this chapter
Vendrig, D.E.M.M., Mekking, A., Teeuwsen, J., Holthuis, J.J.M. (1988). The Stability of Antineoplastic Vinca Alkaloids in Plasma and Urine. In: Reid, E., Robinson, J.D., Wilson, I.D. (eds) Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular. Methodological Surveys in Biochemistry and Analysis, vol 18 A. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9424-3_40
Download citation
DOI: https://doi.org/10.1007/978-1-4757-9424-3_40
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-9426-7
Online ISBN: 978-1-4757-9424-3
eBook Packages: Springer Book Archive