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The Stability of Antineoplastic Vinca Alkaloids in Plasma and Urine

  • D. E. M. M. Vendrig
  • A. Mekking
  • J. Teeuwsen
  • J. J. M. Holthuis
Part of the Methodological Surveys in Biochemistry and Analysis book series (MSBA, volume 18 A)

Abstract

Vinblastine and vincristine (Fig. 1) are naturally occurring vinca alkaloids present in the Madagascar Periwinkle plant. Vindesine is a semi-synthetic vinca alkaloid, derived from vinblastine. The vinca alkaloids are active against various types of cancer, e.g. Hodgkin’s disease, lymphomas and testicular carcinoma [1].

Keywords

Vinca Alkaloid Concentration Decrease Blank Plasma Repeated Freezing Testicular Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • D. E. M. M. Vendrig
    • 1
  • A. Mekking
    • 1
  • J. Teeuwsen
    • 1
  • J. J. M. Holthuis
    • 1
  1. 1.Department of Pharmaceutical AnalysisUniversity of UtrechtUtrechtThe Netherlands

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