Abstract
Brief mention is made of the assay and stereoselective metabolism of ibuprofen. The NSAIDā½ given attention in this article is flurbiprofen, the development of which entailed successive assay methods. That outlined below was used when the number of samples to be assayed was escalating.
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Abbreviations
- NSAID:
-
non-steroidal anti-inflammatory drug
- PFB:
-
pentafluorobenzyl
- RP:
-
reversed phase
- i.s.:
-
internal standard
References
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Ā© 1988 Springer Science+Business Media New York
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Bye, A., Adams, W., Kaiser, D. (1988). Analytical Approaches Adopted during the Development of Flurbiprofen. In: Reid, E., Robinson, J.D., Wilson, I.D. (eds) Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular. Methodological Surveys in Biochemistry and Analysis, vol 18 A. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9424-3_12
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