Bee Products pp 179-183 | Cite as

The Use of Royal Jelly During Treatment of Childhood Malignancies

  • Osman Kaftanoglu
  • Atilla Tanyeli


Eight children who have malign diseases such as acute leukemia, lymphoma and hepatoblastoma were included in this preliminary study. All the patients had 1 gram of royal jelly (RJ) before breakfast once a day for one month. During this period complete blood counts, general condition and weights of the patients were recorded. The values of the same patients before and after the use of RJ were examined as controls. The patients did not have GM-CSF and G-CSF while they were having RJ.

The average hematocrit values did not differ before and after the use of RJ. The average white blood cells increased from 2,857±388 to 3,732±366; neutrophils from 1,489±367 to 2,647±620; and lymphocytes from 1,137±180 to 1,665±255 after using RJ. The general conditions (having an appetite and feeling better) increased and weight gain were observed after RJ administrations. The patients who had RJ gained an average of 1.737±0.725 kg weight after one month.


White Blood Cell Granulocyte Colony Stimulate Factor Acute Leukemia Royal Jelly Acute Myeloblastic Leukemia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Saikatsu, S., Ikeno, K., Hanada, Y., Ikeno, T. (1989) Physiologically active substances in oral secretions produced by the honey bee-effects of royal jelly on the silkworm. Ohu Univ. Dental J. 61(3): 1–4 (In Japanese).Google Scholar
  2. 2.
    Afifi, E. A., Khattab, M.M., El-Berry, A.A., Abdel-Gawaad, A.A. (1989) Effect of royal jelly on guinea-pig growth. Proceedings of the Fourth International Conference on Apiculture in Tropical Climates, Cairo, Egypt, 6–10 Nov. 1988.Google Scholar
  3. 3.
    Blum, M.S., Novak, A.F., Taber, S. (1959). 10-hydroxy-2-decenoic acid, an antibiotic found in royal jelly. Science 130(3373): 452–453.CrossRefGoogle Scholar
  4. 4.
    Serra Bonvehi, J., Escola Jorda, R. (1991) Studie über die mikrobiologische qualitat und bakteriostatische aktivitat des weiselfuttersaftes (Gelee Royale):Beeinflussung durch organische sauren. Deutsche Lebensmittel-Rundschau 87(8):256–259.Google Scholar
  5. 5.
    Fujiwara, S., Imai, J., Fujiwara, M., Yaeshima, T., Kawashima, T., Kobayashi, K. (1990) A potent antibacterial protein in royal jelly. Purification and determination of the primary structure of royalisin. J. Biol. Chem. 265(19): 11333–11337.Google Scholar
  6. 6.
    Tamura, T., Fujii, A., Kuboyama, N. (1987) Anti-tumor effects of royal jelly. Nippon Yakurigaku Zasshi 89(2) 73–80 (In Japanese).CrossRefGoogle Scholar
  7. 7.
    Yamada, K., Ikede, I., Maeda, M., Shirahata, S., Murakami, H. (1990) Effect of immunoglobulin production stimulating factors in foodstuffs on immunoglobulin production of human lymphocytes. Agricultural and Biological Chemistry 54(4): 1087–1089.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Osman Kaftanoglu
    • 1
  • Atilla Tanyeli
    • 2
  1. 1.Faculty of AgricultureUniversity of CukurovaAdanaTurkey
  2. 2.Faculty of MedicineUniversity of CukurovaAdanaTurkey

Personalised recommendations