Stability of Components of the Escherichia coli Septator
Most of the information concerning cell division in Escherichia coli derive from genetic observations. Mutations in E. coli genes causing inhibition of cell division and a filamentous phenotype have been isolated (Bachmann, 1990). In this way, several genes have been identified and among them, ftsQ (Begg et al., 1980), ftsA (Donachie et al., 1979) and ftsZ (Lutkenhaus et al., 1980) seem specially relevant for the initial (ftsQ and ftsZ) and final (ftsA) steps of the process. FtsQ, FtsA and FtsZ have been located associated to different degrees to the cytoplasmic membrane, and have been postulated to form part of the septator, a structure active in cell division (Vicente et al., 1991 b).
KeywordsCell Division Protein FtsZ Ring Transcriptional Organization Lambda Repressor Western Type Blot
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