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Disturbance of Peptidoglycan Synthesis by Glycine and D-Methionine Creates a Signal for the ampG-Mediated Induction of AmpC-β-Lactamase in Escherichia coli

  • Hans H. Martin
  • Herbert Schmidt
Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 65)

Abstract

It has been reasoned that bacterial β-lactamases must have a “normal” physiological function, apart from inactivating β-lactam antibiotics, probably connected to the metabolism of cell wall peptidoglycan (Abraham and Chain, 1940; Saz and Lowery, 1979). In the same context, evidence has been brought forward which points to an essential role of peptidoglycan metabolism in the induced synthesis of β-lactamase in Gram-positive and Gram-negative bacteria (Collins, 1979; Tuomanen et al., 1991).

Keywords

Enterobacter Cloaca Shake Culture Cell Wall Peptidoglycan Citrobacter Freundii Peptidoglycan Synthesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Hans H. Martin
    • 1
  • Herbert Schmidt
    • 1
  1. 1.Institut für MikrobiologieTechnische HochschuleDarmstadtGermany

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