Advertisement

An Overview of the Assembly, Turnover and Recycling of the Murein Sacculus

  • James T. Park
Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 65)

Abstract

In presenting an overview of this subject, I will limit my remarks to the situation in E. coli. The discussion is divided into two parts.

Keywords

Lateral Wall Cell Elongation Restrictive Temperature Peptidoglycan Synthesis Cell Septation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Barbas, J. A., Diaz. J., Rodriguez-Tebar, A. and Vazquez, D. (1986) Specific location of penicillin-binding proteins within the cell envelope of Escherichia coli. J. Bacteriol. 165, 269–275.PubMedGoogle Scholar
  2. Begg, K. J., Spratt, B. G. and Donachie, W. D. (1986) Interaction between membrane proteins PBP 3 and RodA is required for normal cell shape and division in Escherichia coli. J. Bacteriol. 167, 1004–1008.PubMedGoogle Scholar
  3. Botta, G. A. and Park, J. T. (1981) Evidence for involvement of penicllin-binding protein 3 in murein synthesis during septation but not during cell elongation. J. Bacteriol. 145, 333–340.PubMedGoogle Scholar
  4. Burman, L. and Park, J. T. (1984) Molecular model for elongation of the murein sacculus of Escherichia coli. Proc. Nalt. Acad. Sci. U.S.A. 81, 1844–1848.CrossRefGoogle Scholar
  5. Cooper, S., Hsieh, M.-L. and Guenther, B. (1988) Mode of peptidoglycan synthesis in Salmonella typhimurium: single-strand insertion. J. Bacteriol. 170, 3509–3512.PubMedGoogle Scholar
  6. de la Rosa, E. J., de Pedro, M. A. and Vazquez, D. (1985) Penicillin binding proteins: role in initiation of murein synthesis in Escherichia coli. Proc. Natl. Acad. Sci. USA 82, 5632–5635.PubMedCrossRefGoogle Scholar
  7. de Jonge, B. L. M., Wientjes, F. B., Jurida, I., Driehuis, F., Wouters, J. T. M. and Nanninga, N. (1989) Peptidoglycan synthesis during the cell cycle of Escherichia coli: composition and mode of insertion. J. Bacteriol. 171, 5783–5792.PubMedGoogle Scholar
  8. del Portillo, F. G. and de Pedro, M. A. (1990) Differential effect of mutational impairment of penicillin-binding proteins 1A and 1B on Escherichia coli strains harboring thermosensitive mutations in the celll division genes ftsA, JtsQ, ftsZ, and pbpB. J. Bacteriol. 172, 5863–5870.Google Scholar
  9. del Portillo, F. G., de Pedro, M. A., Joseleau-Petit, D. and D’Ari, R. (1989) Lytic response of Escherichia coli cells to inhibitors of penicillin-binding proteins la and lb as a timed event related to cell division. J. Bacteriol. 171,4217–4221.Google Scholar
  10. Goodell, E. W. (1985) Recycling of murein by Escherichis coli. J. Bacteriol. 163, 305–310.PubMedGoogle Scholar
  11. Goodell, E. W. and Schwarz, U. (1985) Release of cell wall peptides into culture medium by exponentially growing Escherichia coli. J. Bacteriol. 162, 391–397.PubMedGoogle Scholar
  12. Goodell, E. W. and Higgins, C. F. (1987) Uptake of cell wall peptides by Salmonella typhimurium and Escherichia coli. J. Bacteriol. 169, 3861–3865.PubMedGoogle Scholar
  13. Izaki, K. and Strominger, J. L.(1968) Biosynthesis of the peptidoglycan of bacterial cell walls. XIV. purification and properties of two D-alanine carboxypeptidases from Escherichia coli. J. Biol. Chem. 243, 3193–3201.PubMedGoogle Scholar
  14. James, R., Haga, J. Y. and Pardee, A. B. (1975) Inhibition of an early event in the cell division cycle of Escerichia coli by FL1060, an amidinopenicillanic acid. J. Bacteriol. 122, 1283–1292.PubMedGoogle Scholar
  15. Keck, W. and Schwarz, U. (1979) Escherichia coli murein DD-endopeptidase insensitive to β-lactam antibiotics. J. Bacteriol. 139, 770–774.PubMedGoogle Scholar
  16. Labischinski, H., Goodell, E. W., Goodell, A. and Hochberg, M. L. (1991) Direct proof of a “more-than-single-layered” peptidoglycan architecture of Escherichia coli W7: a neutron small angle scattering study. J. Bacteriol. 173, 751–756.PubMedGoogle Scholar
  17. Lund, F. and Tybring, L. (1972) 6β-amidinopenicillanic acids—a new group of antibiotics. Nature New Biol. 236, 135–137.PubMedGoogle Scholar
  18. Mett, H., Keck, W., Funk, A. and Schwarz, U. (1980) Two differing species of murein transglycosylase in Escherichia coli. J. Bacteriol. 144, 45–52.PubMedGoogle Scholar
  19. Nakagawa, J., Tamaki, S., Tomioka, S. and Matsuhashi, M. (1984) Functional biosynthesis of cell wall peptidoglycan by polymorphic bifunctional polypeptides. J. Biol. Chem. 259, 13937–13946.PubMedGoogle Scholar
  20. Park, J. T. (1988) Does Escherichia coli use a left-handed murein endopeptidase and transpeptidase to assemble its sacculus? in “Antibiotic inhibition of bacterial cell surface assembly and function” (Actor, P., Daneo-Moore, L., Higgins, M. L., Salton, M. R. J. and Shockman, G. D., Eds), pp.60-65. Soc. for Microbiol., Washington, D.C.Google Scholar
  21. Park, J. T. and Burman, L. (1973) FL1060: a new penicillin with a unique mode of action. Biochem. Biophys. Res. Commun. 51, 863–868.PubMedCrossRefGoogle Scholar
  22. Parquet, C, Fouret, B., Leduc, M., Hirota, Y. and van Heijenoort, J. (1983) N-acetylmuramoyl-L-alanine amidase of Escherichia coli K12. Possible physiological functions. Eur. J. Biochem. 133, 371–377.Google Scholar
  23. Pisabarro, A. G., del Portillo, F. G., de la Rosa, E. J. and de Pedro, M.A. (1987) Initiation of murein biosynthesis in Escherichia coli cells treated with β-lactam antibiotics. FEMS Microbiol. Lett. 42, 81–84.Google Scholar
  24. Rodriguez, M. C. and de Pedro, M. A. (1990) Initiation of growth in pbpA ts and rodA ts mutants of Escherichia coli. FEMS Microbiol. Lett. 72, 235–240.CrossRefGoogle Scholar
  25. Schmidt, L. S., Botta, G. and Park, J. T. (1981) Effects of furazlocillin, a β-lactam antibiotic which binds selectively to penicillin-binding protein 3, on Escherichia coli mutants deficient in other penicillin-binding proteilns. J. Bacteriol. 145, 632–637.PubMedGoogle Scholar
  26. Spratt, B. G. (1975) Distinct penicillin binding proteins involved in the division, elongation, and shape of Escherichia coli K12. Proc. Natl. Acad. Sci. USA 72,2999–3003.PubMedCrossRefGoogle Scholar
  27. Suzuki, H., Nishimura, Y. and Hirota, Y. (1978) On the process of cellular division in Escherichia cloi a series of mutants of E. coli altered in the penicillin-binding proteins. Proc. Natl. Acad. Sci. USA 75, 664–668.PubMedCrossRefGoogle Scholar
  28. Tamura, T., Imae, Y. and Strominger, J. L. (1976) Purification to homogeniety and properties of two D-alanine carboxypeptidases from Escherichia coli J. Biol. Chem. 251, 414–423.Google Scholar
  29. Tuomanen, E. and Schwartz, J. (1987) Penicillin-binding protein 7 and its relationship to lysis of nongrowing Escherichia coli. J. Bacteriol. 169,4912–4915.PubMedGoogle Scholar
  30. Wientjes, F. B., Woldringh, C. L. and Nanninga, N. (1991) Amount of peptidoglycan in cell walls of gram-negative bacteria. J. Bacteriiol. 173, 7684–7691.Google Scholar
  31. Woldringh, C. L., Huis, P., Pas, E., Brakenhoff, G. J. and Nanninga, N. (1987) Topography of peptidoglycan synthesis during elongation and polar cap formation in a cell division mutant of Escherichia coli MC4100. J. Gen. Microbiol. 133, 575–586.Google Scholar

Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • James T. Park
    • 1
  1. 1.Department of Molecular Biology and MicrobiologyTufts University School of MedicineBostonUSA

Personalised recommendations