Virus Variation and the Epidemiology and Control of Rhinoviruses
As a background to this chapter it seems important to give first a brief outline of current concepts of the basic structure, biology, and replication of rhinoviruses since these have been changing fast recently. How these affect the epidemiology and the possibility of control by drugs or vaccines will then be discussed. The aim will be to show how changes in the nucleotide sequences of the genetic material are reflected in the behavior of the virus at the biologic level, as it interacts with the host and environment, produces disease, and provides an immune response. We have not reached that point yet, but there is interesting and encouraging progress to report.
KeywordsVirus Particle Common Cold Virus Capsid Human Seron Monkey Kidney Cell
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