Current Electron Microscopic Methods in Diagnostic Virology

  • Robert D. O. Devine
Part of the Applied Virology Research book series (AVIR, volume 3)


The development of electron microscopy as applied to diagnostic virology began with the occasional, yet nonetheless urgent, need to differentiate herpes zoster infections from mild or atypical variola. Laboratory methods had been designed to identify these viruses but only electron microscopy enabled the differentiation to be made within minutes of receiving the clinical specimens. A description of the electron microscopic procedures used to successfully identify herpes zoster or variola in vesicular fluid specimens taken from infected patients was published in 1948 by Nagler and Rake.


Herpes Zoster Clinical Specimen Immunoelectron Microscopy Vesicle Fluid Molluscum Contagiosum 


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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Robert D. O. Devine
    • 1
  1. 1.Provincial Laboratory of Public HealthUniversity of AlbertaEdmontonCanada

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