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Ultrasensitive Sub-Nanosecond Time-Gated Detection Using a Single Photon Avalanche Diode

  • Lloyd M. Davis
  • Li-Qiang Li

Abstract

Ultrasensitive detection and spectroscopy experiments require single photon detectors with sub-nanosecond timing jitter. Since the first experiments demonstrating the detection of single chromophore dye molecules in solution,1 a significant improvement in the signal rate from each molecule has been achieved by using a high quantum efficiency single photon avalanche diode (SPAD). The EG&G SPCM-200 SPAD with custom-modified passivelyquenched bias circuit has been characterized for this purpose2 and has been found to provide a quantum efficiency of 55% at 532 nm and a single photon timing jitter of 168 ps when the input light is focused to a spot of diameter < 20 µm.

Keywords

Dead Time Time Spectrum Single Photon Detector Single Molecule Detection Fluorescence Photon 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    E. B. Shera, N. K. Seitzinger, L. M. Davis, R. A. Keller, and S. A. Soper, “Detection of single fluorescent molecules,” Chem. Phys. Lett. 174:553 (1990).CrossRefGoogle Scholar
  2. 2.
    L. Q. Li and L. M. Davis, “Single photon avalanche diode for single molecule detection,” Rev. Sci. Instrum. 64:1524 (1993).CrossRefGoogle Scholar
  3. 3.
    L. Q. Li and L. M. Davis, “Single molecule detection for analytical applications,” Opt. Soc. Am. Tech. Dig. 16:1 (1993).Google Scholar
  4. 4.
    S. A. Soper, L. M. Davis, and E. B. Shera, “Detection and identification of single molecules in solution,” J. Opt. Soc. Am. B 9:1761 (1992).CrossRefGoogle Scholar
  5. 5.
    L. M. Davis and L. Q. Li, “Monte Carlo model of a single molecule counting experiment,” Opt. Soc. Am. Tech Dig. 5:206 (1994).Google Scholar

Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Lloyd M. Davis
    • 1
  • Li-Qiang Li
    • 1
  1. 1.Center for Laser ApplicationsUniversity of Tennessee Space InstituteTullahoma

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