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Antibiotics pp 255-263 | Cite as

Antibiotics and Producer Organisms

  • Giancarlo Lancini
  • Francesco Parenti
  • Gian Gualberto Gallo

Abstract

The relationship between antibiotics and their producer microorganisms is a matter of lively discussion among specialists. Why is the ability to produce a great variety of antibiotics limited to relatively few classes of microorganisms? How can a producer organism survive in the presence of a substance toxic to it? What is the “natural” function of antibiotics, i.e., what evolutionary advantage do they confer to the producer? There are no generally accepted answers to these questions.

Keywords

Secondary Metabolite Antibiotic Production Evolutionary Advantage Streptomyces Griseus Lively Discussion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Reference

  1. Cundliffe, E., 1989How antibiotic-producing organisms avoid suicide Annu. Rev. Microbiol. 43:207. Google Scholar
  2. Davies, J., 1990What are antibiotics? Archaic functions for modern activities Mol. Microbiol.4:1227. Google Scholar
  3. Demain, A. L., 1989, Functions of secondary metabolites, in Genetics and Molecular Biology of Industrial Microorganisms ( C. L. Herschberger, S. W. Queener, and G. Hegeman, eds.), pp. 1–11, American Society for Microbiology, Washington, D.C.Google Scholar
  4. Laskin, A. I., and Lechevalier, H. A. (eds.), 1988, Handbook of Microbiology, 2nd ed., Vol. 9, Part A, CRC Press, Boca Raton, Fla.Google Scholar
  5. Martin, J. F., and Liras, P., 1989, Organization and expression of genes involved in the biosynthesis of antibiotics and other secondary metabolites, Anna. Rev. Microbiol. 43: 173.CrossRefGoogle Scholar
  6. Stone, M. J., and Williams, D. H., 1992, On the evolution of functional secondary metabolites, Mol. Microbiol., 6: 29.PubMedCrossRefGoogle Scholar
  7. Vining, L. C., 1990, Functions of secondary metabolites, Anna. Rev. Microbiol. 44: 395.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1995

Authors and Affiliations

  • Giancarlo Lancini
    • 1
  • Francesco Parenti
    • 2
  • Gian Gualberto Gallo
    • 1
  1. 1.Lepetit Research CenterMarion Merrell Dow Research Institute (MMDRI)GerenzanoItaly
  2. 2.Marion Merrell Dow Europe AGHorgenSwitzerland

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