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Expression of the M-Subunit of Laminin Correlates with Increased Cell Adhesion and Metastatic Propensity

  • Wheamei Jenq
  • Shi-Jun Wu
  • Nicholas A. Kefalides
Chapter
Part of the NATO ASI Series book series (NSSA, volume 263)

Abstract

The presence of several isoforms of laminin in a variety of tissues and species has been reported. S-laminin, a B1 chain homologue of 190 kDa, has been identified in association with the synaptic cleft of the neuromuscular junction (Hunter, et al., 1989), while O’Rear (1992) has reported a novel laminin B1 chain variant (B1-2) in the avian eye, and Marinkovich et al. (1992) reported another variant, K-laminin in human amniotic fluid.

Keywords

Human Placenta Human Amniotic Fluid Slot Blot Hybridization Metastatic Propensity Placental Basement Membrane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Wheamei Jenq
    • 1
  • Shi-Jun Wu
    • 1
  • Nicholas A. Kefalides
    • 1
  1. 1.Connective Tissue Research Institute and Department of MedicineUniversity of Pennsylvania, and University City Science CenterPhiladelphiaUSA

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