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Angiogenesis pp 449-457 | Cite as

“CM101 — An Anti-Pathoangiogenic Agent: Pre-Clinical and Clinical Experiences”

  • Carl G. Hellerqvist
Chapter
Part of the NATO ASI Series book series (NSSA, volume 298)

Abstract

The pathophysiology of Group B Streptococcal (GBS) disease depends on the age of the neonate infected. Neonates infected at birth by GBS colonizing the birth canal may be diagnosed with early-onset disease. The symptoms are respiratory distress and cardiovascular shock (Baker and Edwards, 1995) and the gravity may vary from asymptomatic to lethal. In infants older than 1 week, late-onset disease is often associated with meningitis. GBS rarely affects normal adults, but may present in old adults with impaired peripheral circulation (diabetics) or with a compromised immune system due to cancer or other debilitating disease (Farley, Harvey, Stull, Smith, Schuchat, Wenger, and Stephens, 1993).

Keywords

Complement Receptor Type Tumor Neovasculature Young Lamb Minute Time Point Cardiovascular Shock 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Carl G. Hellerqvist
    • 1
  1. 1.Department of BiochemistryVanderbilt University School of MedicineNashvilleUSA

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