Advertisement

Angiogenesis pp 137-147 | Cite as

Role of Fibroblast Growth Factor -2 and Endothelial Cell Stimulating Angiogenic Factor (ESAF) in Capillary Growth in Skeletal Muscles Exposed to Long-Term High Activity

  • M. D. Brown
  • H. Walter
  • O. Hudlicka
  • F. M. Hansen-Smith
  • J. B. Weiss
Chapter
Part of the NATO ASI Series book series (NSSA, volume 298)

Abstract

Angiogenesis, the development of new blood vessels, is a process controlled by many different mediators, of which different growth factors have been considered to be key regulators. In particular, fibroblast growth factors (FGFs) are known to be involved in angiogenesis in many pathological situations e.g. tumours (Folkman and Klagsbrun, 1987), wound healing (Broadley, Aquino, Woodward, Buckley-Sturrock, Sato, Rifkin and Davidson, 1989), inflammatory conditions (D’Amore, 1992), growth of collateral vessels in ischaemic heart (Schaper, Sharma, Quinkler, Markert, Wünsch and Schaper, 1990) and skeletal muscle (Yang, Deschenes, Ogilvie and Terjung, 1996). However, FGFs do not appear to cause proliferation of endothelial cells in uninjured tissue (D’Amore, 1990) and it has therefore not been established whether they play a role in angiogenesis under normal physiological conditions when the microvascular bed is undamaged. During development, FGFs may be involved in vasculogenesis in the heart (Tomanek, Haung, Suvarna, O’Brien, Ratajska and Sandra, 1996), but in skeletal muscle, angiogenesis during postnatal growth does not seem to be associated with basic fibroblast growth factor FGF-2 (Hansen-Smith, Morris and Joswiak, 1992).

Keywords

Skeletal Muscle Tibialis Anterior Basic Fibroblast Growth Factor Extensor Digitorum Longus Extensor Digitorum Longus Muscle 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Broadley, K.N., Aquino, A.M., Woodward, S.C., Buckley-Sturrock, A., Sato, Y., Rifkin, D.B. and Davidson, J.M., 1989, Monospecific antibodies implicate basic fibroblast growth factor in normal wound repair, Lab. Invest. 61: 571–575.PubMedGoogle Scholar
  2. Brown, M.D., Cotter, M.A., Hudlická, O. and Vrbova, G., 1976, The effect of different patterns of muscle activity on capillary density, mechanical properties and structure of slow and fast rabbit muscles, Pflügers Arch. 361: 315–323.CrossRefGoogle Scholar
  3. Brown, M.D., Hudlická, O., Makki, R.F. and Weiss, J.B., 1995, Low-molecular-mass-endothelial cell-stimulating angiogenic factor in relation to capillary growth induced in rat skeletal muscle by low-frequency electrical stimulation, Int. J. Microcirc. 15: 111–116.CrossRefGoogle Scholar
  4. Brown, M.D., Hudlická, O., Damon, D. and Duling, B.R., 1996, Vasoactive effects of basic and acidic fibroblast growth factors in hamster cheek pouch arterioles, Int. J. Microcirc. 16: 308–312.CrossRefGoogle Scholar
  5. Chomcyznski, P. and Sacchi, N., 1987, Single-step method of RNA isolation by guanidinium thiocyanate -phenol-chloroform extraction, Anal. Biochem. 162: 156–159.Google Scholar
  6. D’Amore, P.A., 1990, Modes of FGF release in vivo and in vitro, Cancer and Metast. Rev. 9: 227–238.CrossRefGoogle Scholar
  7. D’Amore, P.A., 1992, Mechanism of endothelial growth control, Am. J. Resp. Cell. Mol. Biol. 6: 1–8CrossRefGoogle Scholar
  8. Dawson, J.M. and Hudlická, O., 1989, The effect of long-term activity on the microvasculature of rat glycolytic skeletal muscle, Int. J. Microcirc. 8: 53–69.Google Scholar
  9. Folkman, J. and Klagsbrun, M., 1989, Angiogenic factors, Science 235: 442–446.CrossRefGoogle Scholar
  10. Folkman, J. and Shing, Y., 1992, Angiogenesis, J. Biol. Chem. 267: 10931–10934.PubMedGoogle Scholar
  11. Gonzales, A.M., Berry, M., Maher, P.A., Logan, A. and Baird, A., 1995, A comprehensive analysis of the distribution of FGF-2 and FGFR1 in the rat brain, Brain Res. 701: 201–226.CrossRefGoogle Scholar
  12. Hansen-Smith, F.M., Watson, L., Lu, D.Y. and Goldstein, I., 1988, Griffonia simplicifolia I: fluorescent tracer for microcirculatory vessels in nonperfused thin muscles and sectioned muscle, Microvasc. Res. 36: 199–215.PubMedCrossRefGoogle Scholar
  13. Hansen-Smith, F.M., Morris, L. and Joswiak, GR., 1992 Postnatal proliferation of microvessels and the distribution of basic fibroblast growth factor (bFGF) in rat sternomastoid muscle, FASEB J. 6: Al600Google Scholar
  14. Hansen-Smith, F.M., Hudlická, O. and Egginton, S., 1996, In vivo angiogenesis in adult rat skeletal muscle: early changes in capillary network architecture and ultrastructure, Cell Tissue Res. 286: 123–136.PubMedCrossRefGoogle Scholar
  15. Hudlická, O., Brown, M.D. and Egginton, S., 1992, Angiogenesis in skeletal and cardiac muscle, Physiol. Rev. 72: 369–417.PubMedGoogle Scholar
  16. Hudlická, O., Brown, M.D., Walter, H., Weiss, J.B. and Bate, A., 1995, Factors involved in capillary growth in the heart, Mol.and Cell. Biochem. 147: 57–68.CrossRefGoogle Scholar
  17. Lexell, T., Jarvis, J., Downham, D. and Salmons, S., 1992, Quantitative morphology of stimulation-induced damage in rabbit fast twitch skeletal muscles. Cell Tiss. Res. 269: 195–204.CrossRefGoogle Scholar
  18. Maniatis, T., Fritsch, E.F. and Sambrook, J., 1982, Molecular cloning: a laboratory manual, Cold Spring Harbour Laboratory, New York.Google Scholar
  19. McLaughlin, B. and Weiss, J.B., 1996, Endothelial-cell-stimulating angiogenesis factor (ESAF) activates progelatinase A (72kDa type IV collagenase), prostromelysin 1 and procollagenase and reactivates their complexes with tissue inhibitors of metalloproteinases: a role of ESAF in non-inflammatory angiogenesis, Biochem. J. 317: 739–745.PubMedGoogle Scholar
  20. Morrow, N.G., Kraus, W.E., Moore, J.W., Williams, R.S. and Swain, J.L., 1990, Increased expression of fibroblast growth factor in a rabbit skeletal muscle model of exercise conditioning, J. Clin. Invest. 85: 1816–1820.PubMedCrossRefGoogle Scholar
  21. Myrhage, R. and Hudlická, O., 1978, Capillary growth in chronically stimulated adult skeletal muscles as studied by intravital microscopy and histological methods in rabbits and rats, Microvasc. Res. 16: 73–90.PubMedCrossRefGoogle Scholar
  22. Odedra, R. and Weiss, J.B., 1991, Low molecular weight angiogenesis factors, Pharmacol. Ther. 49: 111–124.PubMedCrossRefGoogle Scholar
  23. Pearce, S. and Hudlická, O., 1994, Are prostaglandins involved in capilary growth in chronically stimulated muscles ? Int. J. Microcirc. 14: 243.Google Scholar
  24. Pearce, S., Hudlická, O. and Egginton, S., 1995, Early stages in activity induced angiogenesis in rat skeletal muscle: incorporation of bromodeoxyuridine into cells of the interstitium, J. Physiol. 483: 143 PGoogle Scholar
  25. Pette, D., Müller, W., Leisner, E. and Vrbová, G., 1976, Time dependent effects on contractile properties, fibre population, myosin light chains and enzymes of energy metabolism in intermittently and continuously stimulated fast twitch muscles of the rabbit, Pflügers Archiv. 364: 103–112.PubMedCrossRefGoogle Scholar
  26. Sambrook, J., Fritsch, E.F. and Maniatis, T., 1989, Molecular cloning: a laboratory manual, 2nd ed., Cold Spring Harbor, New York.Google Scholar
  27. Schaper, W., Sharma, H.S., Quinkler, W., Markert, T., Wunsch, M. and Schaper, J., 1990, Molecular biologic concepts on coronary anastamoses, J. Am. Coll. Cardiol. 15: 513–518.PubMedCrossRefGoogle Scholar
  28. Shimasaki, S., Emoto, N., Koba, A., Mercado, M.. Shibata, F.. Cooksey, K.. Baird, A. and Ling N., 1988, Complementary DNA cloning and sequencing of rat ovarian basic fibroblast growth factor and tissue distribution study of its mRNA, 1988, Biochem. Biophys. Res. Commun. 157:256–263.PubMedCrossRefGoogle Scholar
  29. Speir, E., Zilou, V.F., Lee, M., Shrivastav, S. and Casscells, W., 1989, Fibroblast growth factors are present in adult cardiac myocytes in vivo, Biochem. Biophys. Res. Commun. 159: 1336–1340.PubMedGoogle Scholar
  30. Tomanek, R.J., Haung, L., Suvarna, P.R., O’Brien, L.C., Ratajska, A. and Sandra, A., 1996, Coronary vascularization during development in the rat and its relationship to basic fibroblast growth factor, Cardiovasc. Res. 31: E116–E126Google Scholar
  31. Weiss, J.B., Hill, C.R., Davis, R.J., McLaughlin, B., Sedowofia, K.A. and Brown, R.A, 1983, Activation of a procollagenase by low molecular weight angiogenesis factor. Biosci. Rep. 3: 171–177.PubMedCrossRefGoogle Scholar
  32. Yamada, S., Buffinger, N., DiMario, J. and Strohman, R.C., 1989, Fibroblast growth factor is stored in fiber extracellular matrix and plays a role in regulating muscle hypertrophy,Med. Sc. Sports Exerc. 21: S173–S180.Google Scholar
  33. Yang, H.T., Deschenes, M.R., Ogilvie, R.W. and Terjung, R.L., 1996, Basic fibroblast growth factor increases collateral blood flow in rats with femoral arterial ligation, Circ. Res. 79: 62–69.PubMedCrossRefGoogle Scholar
  34. Ziada, A.M.A.R., Hudlická, O., Tyler, K.R. and Wright, A.J.A., 1984, The effect of long-term vasodilatation on capillary growth and performance in rabbit heart and skeletal muscle, Cardiovasc. Res. 18: 724–732.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • M. D. Brown
    • 1
  • H. Walter
    • 2
  • O. Hudlicka
    • 2
  • F. M. Hansen-Smith
    • 3
  • J. B. Weiss
    • 4
  1. 1.School of Sport and Exercise SciencesUniversity of BirminghamUK
  2. 2.Dept. of PhysiologyUniversity of BirminghamUK
  3. 3.Dept. of Biological SciencesOakland UniversityRochesterUSA
  4. 4.Wolfson Angiogenesus Unit, Department of RheumatologyHope HospitalSalfordUK

Personalised recommendations