Treatment Modalities and ANCA in Takayasu’s Arteritis
As other vasculitic-syndromes Takayasu ’s-Arteritis needs a long-term immunosuppressive therapy in order to control disease-activity.As steroids create many problems in the long run other immunosuppressives should be considered. We report 3 cases treated with low-dose methotrexate. In all patients the arteritis was controlled, steroids reduced or stopped. In the effort to find autoantibodies 16 patients were screened for c-/p-ANCA and neutrophil granular enzymes. In no patient a positive result could be obtained.
KeywordsAortic Arch Bolus Therapy General Discomfort Coronary Artery Involvement Vasculitic Disorder
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