Cell Wall-Defective Forms of Nocardia Asteroides Require Tetrahydrobiopterin for Their Growth
An L-dopa-responsive movement disorder with Lewy-like body shares many features with patients suffering from Parkinson’s disease (Kohbata and Beaman, 1991). The cause of Parkinson’s disease remains unknown. An encephalitic virus has been proposed to be an etiologic agent for Parkinson’s disease. Following the pandemic of von Economo’ encephalitis lethargica, many patients were left with clinical features resembling Parkinson’s disease (Caine and Langston, 1983). Numerous attempts to isolate an infective agent were undertaken; some claims were made that a filterable, transmissible and glycerol-resistant microorganisms had been isolated, but it was non-cultivatable on ordinary media under either aerobic or anaerobic conditions (Flexner, 1923).
KeywordsFerrous Sulfate Brain Heart Infusion Brain Heart Infusion Broth Nutrient Factor Rigid Cell Wall
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