Neuroendocrine-Immune Interactions in the Gastrointestinal Tract
Gastrointestinal function is modulated by a complex series of neurohormonal interrelations. There is a great deal of evidence for the neurohormonal influence on various aspects of the immuno-inflammatory response of the gastrointestinal mucosa.1–4 Psychological stress, for example, can influence the symptoms of inflammation in such diseases as inflammatory bowel disease(IBD).5 The intestine contains highly specialized subdivisions of both the neuroendocrine and immune systems, and the mucosal surface is especially well designed to allow for interactions between nerves and the cells of the immune system.
KeywordsInflammatory Bowel Disease Lamina Propria Intestinal Mucosa Vasoactive Intestinal Peptide Immune Effector Cell
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