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Influence of Low Dose Dopamine on the Heart Rate and Ventilatory Responses to Sustained Isocapnic Hypoxia

  • Albert Dahan
  • Denham S. Ward
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 450)

Abstract

In awake humans, acute isocapnic hypoxia causes a rapid increase in both ventilation and heart rate. Although the acute ventilatory response is mediated primarily through a stimulatory drive from the carotid body, the heart rate response is more complex. There is apparently a heart rate depressing drive arising from the carotid bodies (CB), and a stimulation arising from a central effect of hypoxia, stimulation from vagal reflexes from the increased pulmonary ventilation and perhaps an increased drive from the aortic bodies (see ref. 1 for a review).

Keywords

Carotid Body Heart Rate Response Ventilatory Response Central Hypoxia Sustained Hypoxia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Albert Dahan
    • 1
  • Denham S. Ward
    • 2
  1. 1.Departments of Anesthesiology and PhysiologyLeiden University Medical CenterLeidenThe Netherlands
  2. 2.Department of Anesthesiology and Electrical Engineering, School of Medicine and DentistryUniversity of RochesterRochesterUK

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