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A Novel Closed Loop Cryosurgical Device

  • John Dobak
  • Xiaoyu Yu
  • Kambiz Ghaerzadeh
Part of the Advances in Cryogenic Engineering book series (ACRE, volume 43)

Abstract

A novel cryosurgical device has been developed that dramatically improves the cost, convenience, safety, and effectiveness of cryosurgical devices. The device incorporates a mixed gas J-T stage. The fluid mixture is non flammable, non toxic, non corrosive, environmentally safe, and therefore suitable for medical applications. The system is compressor driven utilizing a novel oil free motor. Working temperatures of -115 to -125 °C at pressures of 300 to 350 psi are achieved. Approximately 20 watts of refrigeration are delivered at -120 °C.

The compressor console is portable having a 4 cu-ft volumetric footprint. The cryoprobe has a handle 3.5 cm O.D. and 18 cm length with a probe shaft having a 4 mm O.D. and a 3.5 cm freeze zone. In bench top studies using tissue simulating media (2% gelatin, 98% saline) ice balls of 3.5 – 4.0 cm diameter and 5 cm length with a mass of 48 grams are created. Studies using calf liver tissue in a body temperature water bath show ice balls of similar size and mass (3.5 cm diameter, 48 g). In live goat animal studies, surface temperatures of -115 °C were achieved, and ice balls of 3.8 cm in diameter were created in 10 minutes in the liver. Isotherms below -20 °C were developed at 12 mm radial distance from the probe.

Keywords

Heat Exchanger Cool Capacity Freeze Zone Ofthe Probe Counter Flow Heat Exchanger 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • John Dobak
    • 1
  • Xiaoyu Yu
    • 1
  • Kambiz Ghaerzadeh
    • 1
  1. 1.CryoGen, Inc.San DiegoUSA

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