Localisation and Cloning of Genes Involved in the Export of the A-Protein of Aeromonas salmonicida
The paracrystalline surface protein array of Aeromonas salmonicida is composed of tetragonally arranged subunits of Mr = 50800 (Chu et al., 1991). The gene encoding the A-protein has recently been cloned (Belland and Trust, 1987) and sequenced (Chu et al., 1991), and studies on its 3 dimensional structure have been performed (Dooley et al., 1989). The A-layer is involved in the ability of A. salmonicida to produce disease in fish and it appears to protect the bacteria from the bacteriocidal effect of immune and non-immune serum (Ishiguro et al., 1981; Munn et al., 1982) as well as from phagocytic cells (Trust et al., 1983).
KeywordsCell Surface Hydrophobicity Aeromonas Salmonicida Extracellular Protein Secretion Activity A449 Cell Bacteriocidal Effect
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