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Localisation and Cloning of Genes Involved in the Export of the A-Protein of Aeromonas salmonicida

  • Brian Noonan
  • Sonia Cavaignac
  • Trevor J. Trust
Chapter
Part of the NATO ASI Series book series (NSSA, volume 252)

Abstract

The paracrystalline surface protein array of Aeromonas salmonicida is composed of tetragonally arranged subunits of Mr = 50800 (Chu et al., 1991). The gene encoding the A-protein has recently been cloned (Belland and Trust, 1987) and sequenced (Chu et al., 1991), and studies on its 3 dimensional structure have been performed (Dooley et al., 1989). The A-layer is involved in the ability of A. salmonicida to produce disease in fish and it appears to protect the bacteria from the bacteriocidal effect of immune and non-immune serum (Ishiguro et al., 1981; Munn et al., 1982) as well as from phagocytic cells (Trust et al., 1983).

Keywords

Cell Surface Hydrophobicity Aeromonas Salmonicida Extracellular Protein Secretion Activity A449 Cell Bacteriocidal Effect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Brian Noonan
    • 1
  • Sonia Cavaignac
    • 1
  • Trevor J. Trust
    • 1
  1. 1.Department of Biochemistry and Microbiology and Canadian Bacterial Diseases NetworkUniversity of VictoriaVictoriaCanada

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