Sciatectomic Stimulation of Muscle Arginase and Its Implications
Denervated muscle is characterized by high turnover of proteins, hyperammonemia, degeneration and regeneration of muscle fibers (Shahzad, 1977; Goldspink 1978; Chetty et al, 1980). In view of these conditions an enzyme like arginase, which cleaves L-arginine to L-ornithine and urea was investigated mainly because, its detoxification role in ammoniotoxemia is well established and its role in extra hepatic tissues, where other urea cycle enzymes are absent, still remains to be elucidated.
KeywordsHydrolysis Toxicity Albumin Urea Hydroxide
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