Immunology pp 303-318 | Cite as

Monocyte-Mediated Antibody-Dependent Cellular Cytotoxicity

  • David G. Poplack
  • Diane E. Cole
  • Usha Srinivasan


During the past decade there has been increasing interest in the role of the mononuclear phagocyte in the immune response. It is now appreciated that these cells subserve a variety of important immunologic functions. In addition to their classical function of removing debris (such as senescent cells) from the circulation, mononuclear phagocytes are involved in antigen processing, antimicrobial resistance, antineoplastic activity, mediation of inflammation, control of granulopoiesis, and regulation of the immune response (Poplack and Blaese, 1980).


Systemic Lupus Erythematosus Atopic Dermatitis Aplastic Anemia Chronic Granulomatous Disease Mononuclear Phagocyte 


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Copyright information

© Springer Science+Business Media New York 1984

Authors and Affiliations

  • David G. Poplack
    • 1
  • Diane E. Cole
    • 1
  • Usha Srinivasan
    • 1
  1. 1.Pediatric BranchNational Cancer InstituteBethesdaUSA

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