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Value of Screening for Microalbuminuria in People with Diabetes as Well as in the General Population

  • Bo Feldt-Rasmussen
  • Jan Skov Jensen
  • Knut Borch-Johnsen

Abstract

The concept of microalbuminuria was first introduced among diabetologists [1,2]. It is diagnosed when the urinary albumin excretion rate (UAER) is slightly elevated compared with a normal reference range but lower than what is seen when the classical dipstix are positive for protein or albumin. Microalbuminuria is a marker of an increased risk of diabetic nephropathy and of cardiovascular disease in patients with insulin-dependent (LDDM) as well as with non-insulin-dependent (NDODM) diabetes mellitus [1–18]. A high number of studies of the pathophysiology and of interventional measures in these patients have been published as reviewed in a number of dissertations and reviews since 1989 [19–27] and seven sets of recommendations on the prevention of diabetic nephropathy, with special reference to microalbuminuria have been published [28–34]. More recently microalbuminuria has been brought into a wider perspective because it has been found to be associated with cardiovascular disease also in the non-diabetic population. In fact microalbuminuria may show to be a risk factor of cardiovascular disease among otherwise apparently healthy persons [35–49].

Keywords

Diabetic Nephropathy Urinary Albumin NIDDM Patient nondiabEtic Subject IDDM Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media Dordrecht 1998

Authors and Affiliations

  • Bo Feldt-Rasmussen
    • 1
  • Jan Skov Jensen
    • 1
  • Knut Borch-Johnsen
    • 1
  1. 1.Department of Nephrology, Copenhagen, and Steno Diabetes CenterRigshospitalet University HospitalGentofteDenmark

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