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Abstract

Ever since Cade1 in 1949 first described the use of lithium (Li) in the treatment of psychiatric disorders, much clinical research has focused on controlled testing of various therapeutic indications for its utilization. As recently summarized,2 lithium has been clearly indicated for the acute chemotherapy of mania and the prevention of recurrences of mania and depression; its efficacy in amelioration of depression and schizophrenia is less clear.

Keywords

Bipolar Patient Efflux Rate Constant Brain Uptake Index Tryptophan Hydroxylase Activity Primary Affective Disorder 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • Paul J. Goodnick
    • 1
  • Samuel Gershon
    • 2
  1. 1.Department of Lithium StudiesNew York State Psychiatric InstituteNew YorkUSA
  2. 2.Lafayette Clinic and Department of PsychiatryWayne State University School of MedicineDetroitUSA

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