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Alterations of Metabolites in the Nervous System pp 103–149Cite as

Lithium

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Abstract

Ever since Cade1 in 1949 first described the use of lithium (Li) in the treatment of psychiatric disorders, much clinical research has focused on controlled testing of various therapeutic indications for its utilization. As recently summarized,2 lithium has been clearly indicated for the acute chemotherapy of mania and the prevention of recurrences of mania and depression; its efficacy in amelioration of depression and schizophrenia is less clear.

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Authors and Affiliations

  1. Department of Lithium Studies, New York State Psychiatric Institute, New York, New York, 10032, USA

    Paul J. Goodnick

  2. Lafayette Clinic and Department of Psychiatry, Wayne State University School of Medicine, Detroit, Michigan, 48201, USA

    Samuel Gershon

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  1. Paul J. Goodnick
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  2. Samuel Gershon
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  1. Center for Neurochemistry, Wards Island, New York, USA

    Abel Lajtha

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Goodnick, P.J., Gershon, S. (1985). Lithium. In: Lajtha, A. (eds) Alterations of Metabolites in the Nervous System. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-6740-7_5

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