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Pathology of Axonal Transport

  • W. Graham McLean
  • Martin Frizell
  • Johan Sjöstrand

Abstract

The continuous intraaxonal transport of axoplasmic materials is a major energy-requiring process within the normal nerve cell. Axonal transport provides axons and dendrites with the vast majority, if not all, of their constituent proteins necessary for the formulation of the cytoskeleton, for neurotransmission, and for membrane structure and function. Mechanisms also exist for the axonal transport of lipids, nucleic acids, amino acids, small neurotransmitter molecules, and larger organelles. For a review of axonal transport under normal conditions, see Volume 5, Chapter 17 of this Handbook.

Keywords

Carpal Tunnel Syndrome Sensory Fiber Axonal Transport Optic Nerve Head Retrograde Transport 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • W. Graham McLean
    • 1
  • Martin Frizell
    • 2
  • Johan Sjöstrand
    • 2
  1. 1.Department of Pharmacology and TherapeuticsUniversity of LiverpoolLiverpoolEngland
  2. 2.Departments of Neuropathology and OphthalmologySahlgren’s HospitalGöteborgSweden

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