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The Induction of Sulfatide, Ganglioside and Cerebroside Storage in Organized Nervous System Cultures

  • Jack Stern
  • Alex B. Novikoff
  • Robert D. Terry
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 19)

Abstract

Although a number of animal models exist for the sphingolipidoses, tissue culture offers advantages in studying the development of the inclusion bodies characteristic of these diseases.

Keywords

Dorsal Root Ganglion Neuron Spinal Cord Neuron Residual Body Albert Einstein College Metachromatic Leukodystrophy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Gonatas, N. K. and Gonatas, J. Ultrastructural and biochemical observations on a case of systemic late infantile lipidosis and its relationship to Tay-Sachs disease and gargoylism. J. Neuropath. Exp. Neurol. 24: 318, 1965.PubMedCrossRefGoogle Scholar
  2. 2.
    Grégoire, A., Périer, 0. and Dustin, P. Metachromatic leukodystrophy, an electron microscopic study. J. Neuropath. Exp. Neurol. 25: 617, 1966.CrossRefGoogle Scholar
  3. 3.
    Hirsch, T. von and Peiffer, J. Uber histologische Methoden in der Differential diagnose von Leucodystrophien und Lipidosen. Arch. Psychiat. Nerven Kr. 194: 88, 1955.CrossRefGoogle Scholar
  4. 4.
    Mowry, R.W. Improved procedure for the staining of acidic polysaccharides by Müllers colloidal (Hydrous) ferric oxide and its combination with the Feulgen and the Periodic Acid-Schiff reactions. Lab. Invest. 7: 566, 1958.PubMedGoogle Scholar
  5. 5.
    Nelson, E., Aurebeck, G., Osterberg, K., Berry, J., Jabbour, J. T., and Bornhofen, J. Ultrastructural and chemical studies on Krabbe’s disease. J. Neuropath. Exp. Neurol. 22: 414, 1963.PubMedCrossRefGoogle Scholar
  6. 6.
    Novikoff, A.B. Lysosomes and related particles. In: The Cell. Edited by Brachet, J. and Mirsky, A.E. New York, Acad. Press, 1961.Google Scholar
  7. 7.
    Peterson, E.R., Crain, S.M. and Murray, M.R. Differentiation and prolonged maintenance of bioelectrically active spinal cord cultures (rat, chick and human). Z. Zellforsch. 66: 130, 1965.PubMedCrossRefGoogle Scholar
  8. 8.
    Résibois, A. Electron microscopic study of metachromatic leucodystrophy. III. Lysosomal nature of the inclusions. Acta Neuropath. (Berlin) 13: 149, 1969.PubMedCrossRefGoogle Scholar
  9. 9.
    Suzuki, K., Suzuki, K. and Chen, G.C. Morphological, histochemical and biochemical studies on a case of systemic late infantile lipidosis (Generalized Gangliosidosis). J. Neuropath. Exp. Neurol. 27: 15, 1968.PubMedCrossRefGoogle Scholar
  10. 10.
    Suzuki, K. Ultrastructural study of experimental globoid cells. Lab. Invest. 23: 612, 1970.PubMedGoogle Scholar
  11. 11.
    Terry, R.D. and Weiss, M. Studies in Tay-Sachs disease. II. Ultrastructure of the cerebrum. J. Neuropath. Exp. Neurol. 22: 18, 1963.Google Scholar
  12. 12.
    Yunis, E.J. and Lee, R.E. The ultrastructure of Globoid (Krabbe) Leukodystrophy. Lab. Invest. 21: 415, 1969.Google Scholar

Copyright information

© Springer Science+Business Media New York 1972

Authors and Affiliations

  • Jack Stern
    • 1
  • Alex B. Novikoff
    • 1
  • Robert D. Terry
    • 1
  1. 1.Department of PathologyAlbert Einstein College of MedicineBronxUSA

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