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The Treatment of Estrogen Deficiency in Women at Risk for Breast Cancer and Survivors of the Disease

  • Chapter
Book cover Sex Hormone Replacement Therapy

Part of the book series: Endocrine Updates ((ENDO,volume 8))

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Abstract

Many women choose not to take hormone replacement therapy (HRT) after menopause even though medical indications are present (1–5). Among all menopausal women in the United States, only 20–40% ever take HRT (5). Among those given prescriptions, only 65% continue to take the HRT after the first prescription and only 25% for more than three years (6). Many of these women feel that menopause is a natural transition in life and that menopause-associated problems do not require therapy. Others are fearful of complications such as deep venous thrombosis, pulmonary emboli, and stroke or endometrial and breast cancer. For the estimated 2.5 million survivors of breast cancer in the United States, concern about mammary carcinoma risk strongly influences decision making processes regarding HRT.

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  1. The Department of Medicine, Division of Endocrinology, and The Department of Obstetrics/ Gynecology and the Women’s Place, University of Virginia Health System, Charlottesville, Virginia, 22908, USA

    Richard Santen M.D. & JoAnn V. Pinkerton M.D.

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  1. Richard Santen M.D.
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  2. JoAnn V. Pinkerton M.D.
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  1. Monash Medical Centre, Prince Henry’s Institute of Medical Research, Melbourne, Victoria, Australia

    Henry G. Burger

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Santen, R., Pinkerton, J.V. (2000). The Treatment of Estrogen Deficiency in Women at Risk for Breast Cancer and Survivors of the Disease. In: Burger, H.G. (eds) Sex Hormone Replacement Therapy. Endocrine Updates, vol 8. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-6507-6_4

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