The Conduct of the Trial

  • Christopher J. Bulpitt
Part of the Developments in Biostatistics and Epidemiology book series (DBEP, volume 1)


This chapter considers some of the practical difficulties in performing a trial and the problems that may arise. These may be divided into those that are foreseen and taken account of prior to the start of the trial and those that are unexpected. Murphy’s law states, “If anything can go wrong it will.” This law has been attributed to captain E. Murphy, a development engineer, who applied it first to an individual technician saying, “If there is any way to do it wrong, he will” [167].


Serum Uric Acid Pilot Trial Pill Count Dietary Advice Default Rate 


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Copyright information

© Springer Science+Business Media Dordrecht 1983

Authors and Affiliations

  • Christopher J. Bulpitt
    • 1
    • 2
    • 3
  1. 1.Department of Medical Statistics and EpidemiologyLondon School of Hygiene and Tropical MedicineLondonUK
  2. 2.Royal Postgraduate Medical SchoolLondonUK
  3. 3.Hammersmith HospitalLondonUK

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