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Insulin Resistance and the Metabolic Syndrome

  • Rochelle L. Chaiken

Abstract

Insulin resistance is defined as an impaired biological response to the actions of insulin.1 It was classically described as resistance to insulin mediated glucose uptake in peripheral cells. However, as the metabolic and mitogenic processes of insulin action are better understood, abnormal insulin action in these pathways is being elucidated. Thus, impaired biological response to insulin may be associated with either endogenous or exogenous insulin and can be quantified by changes in several metabolic processes, including carbohydrate, lipid, or protein metabolism or by changes in mitogenic processes.2

Keywords

Insulin Resistance Metabolic Syndrome Insulin Sensitivity Growth Hormone Deficiency Normal Glucose Tolerance 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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  • Rochelle L. Chaiken

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