Production of Radionuclides
Nearly 3000 nuclides are known, of which approximately 2700 are radioactive, and the rest are stable. The majority of radionuclides are artificially produced in the cyclotron and reactor. Some short-lived radionuclides are available from the so-called radionuclide generators in which long-lived parents are loaded and decay to short-lived daughters. The following is a brief description of these sources of radionuclides.
KeywordsThermal Neutron Neutron Capture Reaction Daughter Activity Radionuclide Generator Parent Radionuclide
Unable to display preview. Download preview PDF.
- Colombetti LG. Radionuclide generators. In: Rayudu GVS, ed. Radiotracers for Medical Applications. Boca Raton, Fla: CRC Press; 1983; 1I: 133–168.Google Scholar
- Friedlander G, Kennedy JW, Miller JM. Nuclear and Radiochemistry. 3rd ed. New York: Wiley; 1981.Google Scholar
- Gelbard AS, Hara T, Tilbury RS, Laughlin JS. Recent aspects of cyclotron production of medically useful radionuclides. In: Radiopharmaceuticals and Labelled Compounds. Vienna: IAEA; 1973: 239–247.Google Scholar
- Noronha OPD, Sewatkar AB, Ganatra RD, et al. Fission-produced 99Mo-99mTc generator system for medical use. J Nucl Med Biol. 1976; 20: 32–36.Google Scholar
- Poggenburg JK. The nuclear reactor and its products. Semin Nucl Med. 1974; 4: 229243.Google Scholar
- Saha GB. Miscellaneous tracers for imaging. In: Rayudu GVS, ed. Radiotracers for Medical Applications. Boca Raton, Fla: CRC Press; 1983; I1: 119–132.Google Scholar
- Saha GB. Fundamentals of Nuclear Pharmacy. 3rd ed. New York: Springer-Verlag; 1992.Google Scholar
- Saha GB, Maclntyre WJ, Go RT. Cyclotron and positron emission tomography radiopharmaceuticals for clinical imaging. Semin Nucl Med. 1992; XXII: 150–161.Google Scholar