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Part of the book series: Comprehensive Manuals in Pediatrics ((CM PEDIATRICS))

Abstract

Dermatomyositis is a disease of the connective tissues that is characterized primarily by inflammation of skin and muscles. It is uncommon but not rare. Despite its initial description in 1887, the disease went virtually unnoticed in children until relatively recently. Wedgwood et al. (1953)1 and Banker and Victor (1966)2 kindled new interest with their pioneering clinical and pathologic studies. Since that time, there have been an increasing number of clinical reports and a few efforts at etiologic definition.

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References

  1. Wedgwood RJP, Cook CD Cohen J: Dermatomyositis: Report of 26 cases in children with a discussion of endocrine therapy in 13. Pediatrics 12: 447–466, 1953.

    PubMed  CAS  Google Scholar 

  2. Banker BQ, Victor M: Dermatomyositis (systemic angiopathy) of childhood. Medicine 45: 261–289, 1966.

    Article  PubMed  CAS  Google Scholar 

  3. Ackerman AB: Histologic Diagnosis of Inflammatory Skin Diseases. Lea and Febiger, Philadelphia, 1978.

    Google Scholar 

  4. Carpenter A, Karpati G, Rothman S., et al.: The childhood type of dermatomyositis. Neurology 26: 952–962, 1976.

    Article  PubMed  CAS  Google Scholar 

  5. Whitaker JN, Engel WK: Vascular deposits of immunoglobulin and complement in idiopathic inflammatory myopathy. N Engl J Med 286: 333–338, 1972.

    Article  PubMed  CAS  Google Scholar 

  6. Crowe WE, Bove KE, Levinson JE, et al.: Clinical and pathogenetic implications of histopathology in childhood polydermatomyositis. Arthritis Rheum 25: 126–139, 1982.

    Article  PubMed  CAS  Google Scholar 

  7. Currie S, Saunders M, Knowles M, et al.: Immunologic aspects of polymyositis. Q J Med 157: 63–84, 1971.

    Google Scholar 

  8. Dawkins RL, Mastaglis FL: Cell-mediated cytotoxicity to muscle in polymyositis. N Engl J Med 288: 434–438, 1973.

    Article  PubMed  CAS  Google Scholar 

  9. Pachman LM, Cooke N: Juvenile dermatomyositis: A clinical and immunological study. J Pediatr 96: 226–234, 1980.

    Article  PubMed  CAS  Google Scholar 

  10. Carroll JE, Silverman A, Isobe Y, et al.: Inflammatory myopathy, IgA deficiency, and intestinal malabsorption. J Pediatr 89: 216–219, 1976.

    Article  PubMed  CAS  Google Scholar 

  11. Leddy JP, Griggs RC, Klemperer MR, et al.: Hereditary complement (C2) deficiency with dermatomyositis. Am J Med 58: 83–91, 1975.

    Article  PubMed  CAS  Google Scholar 

  12. Liveson JA, Spielholz NI: Peripheral Neurology; Case Studies in Electrodiagnosis. Davis, Philadelphia, 1979.

    Google Scholar 

  13. Bohan A, Peter JB, Bowman RL, et al.: A computer-assisted analysis of 153 patients with polymyositis and dermatomyositis. Medicine 56: 255–286, 1977.

    Article  PubMed  CAS  Google Scholar 

  14. Sullivan DB, Cassidy JT, Petty R: Dermatomyositis in the pediatric patient. Arthritis Rheum 20: 327–331, 1977.

    PubMed  CAS  Google Scholar 

  15. Fischer TJ, Cipel L, Stiehm ER. Pneumotosis intestinalis associated with fatal childhood dermatomyositis. Pediatrics 61: 127–130, 1978.

    PubMed  CAS  Google Scholar 

  16. Singsen BH, Tedford JC, Platzker ACG, et al.: Spontaneous pneumothorax: A complication of juvenile dermatomyositis. J Pediatr 92: 771–774, 1978.

    Article  PubMed  CAS  Google Scholar 

  17. Schwartz MI, Matthay RA, Sahn SA, et al. Interstitial lung disease in polymyositis and dermatomyositis: Analysis of six cases and review of the literature. Medicine 55: 89–104, 1976.

    Article  Google Scholar 

  18. Jacobs JC: Methotrexate and azathioprine treatment of childhood dermatomyositis. Pediatrics 59: 212–218, 1977.

    PubMed  CAS  Google Scholar 

  19. Gottdiener JS, Sherber HS, Hawley RJ, et al.: Cardiac manifestations in polymyositis. Am J Cardiol 41: 1141–1149, 1978.

    Article  PubMed  CAS  Google Scholar 

  20. Bruce GM: Retinitis in dermatomyositis. Trans Am Ophthalmol Soc 32: 282–295, 1938.

    Google Scholar 

  21. Fruman LS, Ragsdale CG, Sullivan DB, et al.: Retinopathy in juvenile dermatomyositis. J Pediatr 88: 267–269, 1976.

    Article  PubMed  CAS  Google Scholar 

  22. Bitnum S, Daeschner CW, Travis LB, et al.: Dermatomyositis. J Pediatr 64: 10 1131, 1964.

    Google Scholar 

  23. Pirovino M, Neff MS, Sharon E: Myoglobinuria and acute renal failure with acute polymyositis. NY State J Med 79: 764–767, 1979.

    CAS  Google Scholar 

  24. Kagen LJ: Myoglobinemia in inflammatory myopathies. JAMA 237: 1448–1452, 1977.

    Article  Google Scholar 

  25. Miller JJ: Late progression in dermatomyositis in childhood. J Pediatr 83: 543–548, 1973.

    Article  PubMed  Google Scholar 

  26. Steiner RM, Glassman L, Schwartz MW, et al.: The radiologic findings in dermatomyositis of childhood. Radiology 111: 385–393, 1974.

    PubMed  CAS  Google Scholar 

  27. Spencer C, Kornreich H, Bernstein, B, et al.: Three courses of juvenile dermatomyositis, abstracted. Arthritis Rheum 22: 661, 1979.

    Google Scholar 

  28. Jacobs JC: Treatment of dermatomyositis. Arthritis Rheum 20: 338–341, 1977.

    Article  PubMed  Google Scholar 

  29. Fischer TJ, Rachelefsky GS, Klein RB, et al.: Childhood dermatomyositis and polymyositis. Treatment with methotrexate and prednisone. Am J Dis Child 133: 386389, 1979.

    Google Scholar 

  30. Bunch TW: Prednisone and azathioprine for polymyositis. Long term follow-up. Arthritis Rheum 24: 45–48, 1981.

    Article  PubMed  CAS  Google Scholar 

  31. Singsen BH: Plasmapheresis: A pediatric perspective. J Pediatr 98: 232–235, 1981.

    Article  PubMed  CAS  Google Scholar 

  32. Pittsley RA, Shearn MA, Kaufman L: Acute hepatitis B simulating dermatomyositis. JAMA 239: 959, 1978.

    Article  PubMed  CAS  Google Scholar 

  33. Dietzman DE, Schaller JG, Ray G, et al.: Acute myositis with influenza B infection. Pediatrics 57: 255–258, 1976.

    PubMed  CAS  Google Scholar 

  34. Drachman DA, Tuncbay TO: The remote myopathy of trichinosis. Neurology 15: 1127–1135, 1965.

    Article  PubMed  CAS  Google Scholar 

  35. Layzer RB, Shearn MA, Satya-Murti S: Eosinophilic polymyositis. Ann Neurol 1: 65–71 1977.

    Article  PubMed  CAS  Google Scholar 

  36. Askari A, Vignos PJ, Moskowitz RW: Steroid myopathy in connective tissue disease. Am J Med 61: 485–492, 1976.

    Article  PubMed  CAS  Google Scholar 

  37. Bardelas JA, Winkelstein JA, Seto DSY, et al.: Fatal echo 24 infection in a patient with hypogammaglobulinemia: Relationship to dermatomyositis-like syndrome. J Pediatr 90: 396–399, 1977.

    Article  PubMed  CAS  Google Scholar 

  38. Wilfert CM, Buckley RH, Mohanakumar T, et al.: Persistent and fatal central-nervous system echovirus infections in patients with agammaglobulinemia. N Engl J Med 296: 1485–1489, 1977.

    Article  PubMed  CAS  Google Scholar 

  39. Mease PJ, Ochs HD, Wedgwood RJ: Successful treatment of echovirus meningoencephalitis and myositis-fasciitis with intravenous immune globulin therapy in a patient with X-linked aggammaglobulinemia. N Engl J Med 304: 1278–1281, 1981.

    Article  PubMed  CAS  Google Scholar 

  40. Nevins MA, Saran M, Bright, M, et al.: Pitfalls in interpreting serum creatine phosphokinase activity. JAMA 224: 1382–1387, 1973.

    Article  PubMed  CAS  Google Scholar 

  41. Hochberg MC, Koppes GM, Edwards CQ, et al.: Hypothyroidism presenting as a polymyositis-like syndrome. Arthritis Rheum 19: 1363–1366, 1976.

    Article  PubMed  CAS  Google Scholar 

  42. Newman AJ, Lee C: Hypothyroidism simulating dermatomyositis. J Pediatr 97: 772–774, 1980.

    Article  PubMed  CAS  Google Scholar 

  43. Editorial: Lipid storage myopathies. Lancet: 1: 757–758, 1978.

    Google Scholar 

  44. Raifman MA, Bernat M, Lenarsky C: Cold weather and rhabdomyolysis. J Pediatr 93: 970–971 1978.

    Article  PubMed  CAS  Google Scholar 

  45. DiMauro S: Metabolic myopathies. In: Vinken PJ, Bruyn GW (eds.) Handbook of Clinical Neurology, vol. 41. North-Holland, Amsterdam, 1979, pp. 175–234.

    Google Scholar 

  46. Penn AS: Myoglobin and myoglobinuria In: Vinken PJ, Bruyn GW (eds.) Handbook of Clinical Neurology, vol. 41. North-Holland, Amsterdam, 1979, pp. 259–285.

    Google Scholar 

  47. Barnes BE: Dermatomyositis and malignancy. Ann Intern Med 84: 68–76, 1976.

    PubMed  CAS  Google Scholar 

  48. Singsen BH, Waters KD, Siegel SE, et al.: Lymphocytic leukemia, atypical dermatomyositis, and hyperlipidemia in a 4 year old boy. J Pediatr 90: 602–604, 1976.

    Google Scholar 

  49. Zundel WS, Tyler FH: The muscular dystrophies. N Engl J Med 273:537–543; 596–601, 1965.

    Google Scholar 

  50. Phillips PE, Kassan SS, Kagen LJ: Increased toxoplasma antibodies in idiopathic inflammatory muscle disease. Arthritis Rheum 22: 209–214, 1979.

    Article  PubMed  CAS  Google Scholar 

  51. Fernandes L, Swinson DR, Hamilton EDB: Dermatomyositis complicating penicillamine treatment. Ann Rheum Dis 36: 94–95, 1977.

    Article  PubMed  CAS  Google Scholar 

  52. Kass E, Straume S, Munthe E: Dermatomyositis after BCG vaccination. Lancet 1: 772, 1978.

    Article  PubMed  CAS  Google Scholar 

  53. Menard DB, Haddad H, Blain JG, et al.: Granulomatous myositis and myopathy associated with Crohn’s colitis. N Engl J Med 295: 818–819, 1976.

    Article  PubMed  CAS  Google Scholar 

  54. Tang TT, Sedmak GV, Siegesmund KA, et al.: Chronic myopathy associated with coxsackie virus type A9. N Engl J Med 292: 608–611, 1975.

    Article  PubMed  CAS  Google Scholar 

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Jacobs, J.C. (1982). Dermatomyositis. In: Pediatric Rheumatology for the Practitioner. Comprehensive Manuals in Pediatrics. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-6153-5_6

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  • DOI: https://doi.org/10.1007/978-1-4757-6153-5_6

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4757-6155-9

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