Atrial Fibrillation and Stroke: The View from Neurology

  • David G. Sherman


Atrial fibrillation is the most frequent cardiac disorder associated with ischemic stroke. Most, but certainly not all strokes in patients with atrial fibrillation, are due to an embolus dislodged from a left atrial thrombus. A large number of these patients also have cerebrovascular disease that may be responsible for their stroke. Thus the diagnostic dilemma in these patients is to determine which potential stroke mechanism is in fact responsible for their stroke. Once the mechanism is determined a course of rational, if not scientifically proven, therapy can be instituted. What follows is a summary of our current criteria for the diagnosis of cardiogenic brain embolism, observations on the nature of stroke in patients with nonvalvular atrial fibrillation (NVAF), and some recommendations regarding the anticoagulant management of these patients.


Posterior Cerebral Artery Hemorrhagic Transformation Cerebral Embolism Embolic Stroke Cardioembolic Stroke 
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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • David G. Sherman
    • 1
  1. 1.Department of Medicine(Neurology)University of Texas Health Science CenterSan AntonioUSA

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