Clinical Trial Dilemmas and Cerebrovascular Disease

  • Lewis H. Kuller


The death rate due to stroke in the United States and other countries has declined substantially in the past forty years.1, 2 This decline has been accentuated since the introduction of specific antihypertensive therapy. The decrease has been noted in many countries, and apparently is a combination of not completely understood lifestyle factors, which have impinged on the prevalence and type of hypertensive disease and risk of stroke and the efficacy of the treatment of hypertensive disease.


Transient Ischemic Attack Anticoagulation Therapy Carotid Endarterectomy Carotid Stenosis Carotid Artery Stenosis 
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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • Lewis H. Kuller
    • 1
  1. 1.Graduate School of Public Health, Department of EpidemiologyUniversity of PittsburghPittsburghUSA

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