Phospholipid Methylation Participates in H2-Receptor Mediated Stimulation of Adenylate Cyclase in Rat Brain

  • Tomio Segawa
  • Koichiro Ozawa
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 236)


There are now several reports that histamine has the properties of a neurotransmitter in the mammalian central nervous system (1–3). Also, there is substantial evidence that histamine acting on H2-receptors stimulates adenylate cyclase in mammalian brain (4–6).


Adenylate Cyclase Histidine Decarboxylase Histamine Dihydrochloride Crude Mitochondrial Fraction Phospholipid Methylation 
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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Tomio Segawa
    • 1
  • Koichiro Ozawa
    • 1
  1. 1.Department of Pharmacology Institute of Pharmaceutical SciencesHirohsima University School of MedicineMinami-ku, Hiroshima 734Japan

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