The First Neuronal Growth Cones in Insect Embryos
Little is known about the mechanisms that generate neuronal specificity during development. Unraveling these mechanisms will require an understanding at the cellular and molecular level of how individual neurons recognize and interact with one another during development. Whereas mammalian nervous systems have an enormous number of neurons, the simpler nervous systems of invertebrates with their relatively small number of identified neurons can provide excellent model systems for studying neuronal specificity.
KeywordsGrowth Cone Drosophila Embryo Lucifer Yellow Neuronal Growth Cone Selective Affinity
Unable to display preview. Download preview PDF.
- Bray, D., 1982, Filopodial contraction and growth cone guidance, in: Cell Behavior (R. Bellairs, A. Curtis, and G. Dunn, eds.) Cambridge University Press, Cambridge, England, pp. 299–317.Google Scholar
- Goodman, C. S., and Pearson, K. G., 1982, Neuronal Development: Cellular Approaches in Invertebrates (C. S. Goodman and K. G. Pearson, eds.) NRP Bulletin, MIT Press, Cambridge, Massachusetts.Google Scholar
- Goodman, C. S., Raper, J. A., Ho, R., and Chang, S., 1982, Pathfinding by neuronal growth cones in grasshopper embryos, Symp. Soc. Dev. Biol. 40:275–316.Google Scholar
- Goodman, C. S., Bastiani, M. J., Raper, J. A., and Thomas, J. B., 1984, Cell recognition during neuronal development in grasshopper and Drosophila, in: Molecular Bases of Neural Development (W. M. Cowan, ed.), NRP Press, (in press).Google Scholar
- Raper, J. A., and Goodman, C. S., 1982, Transient dye coupling between developing neurons reveals patterns of intercellular communication during embryogenesis, in: Cellular Communication during Ocular Development (J. B. Sheffield and S. R. Hilfer, eds.), Springer-Verlag, New York, pp. 85–96.CrossRefGoogle Scholar
- Raper, J. A., Bastiani, M. J., and Goodman, C. S., 1984b, Pathfinding by neuronal growth cones in grasshopper embryos. IV. The effects of ablating the A and P axons upon the behavior of the G growth cone, J. Neurosci. 4:2239–2345.Google Scholar