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Interleukins 4 and 5: Mechanisms of Action

  • Eva Severinson
  • Hee-Bom Moon
  • Susanne Bergstedt-Lindqvist
  • Ulla Persson
  • Christoph Heusser
  • Janet Stavnezer

Abstract

Interleukins 4 and 5 are two recently described lymphokines, which exist both in mouse and man1–5 Biochemical analysis and molecular cloning have aided in determining their structure as well as their function. It has recently become clear that lymphokines in general are not selective for a certain cell type and that they often have a broad range of activities. Although information regarding these activities is emerging with a very high speed, it is still uncertain what is their primary role in vivo and in what way their synthesis and action are regulated.

Keywords

Spleen Cell Stimulation Index Clone Size Precursor Frequency CTLL Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • Eva Severinson
    • 1
    • 2
    • 3
    • 4
  • Hee-Bom Moon
    • 1
    • 2
    • 3
    • 4
  • Susanne Bergstedt-Lindqvist
    • 1
    • 2
    • 3
    • 4
  • Ulla Persson
    • 1
    • 2
    • 3
    • 4
  • Christoph Heusser
    • 1
    • 2
    • 3
    • 4
  • Janet Stavnezer
    • 1
    • 2
    • 3
    • 4
  1. 1.Dept. of Immunol.Stockholm Univ.Sweden
  2. 2.Dept. of Clin. Immunol.Karolinska HospitalStockholmSweden
  3. 3.Pharma ResearchCiba-Geigy Ltd.BaselSwitzerland
  4. 4.Dept. of Microbiol. and Mol. Biol.Univ. of Massachusetts Med. SchoolWorcesterUSA

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