Relative Adrenal Insufficiency Syndrome

  • J. J. M. Ligtenberg
  • J. G. Zijlstra


Several recent studies have given rise to optimism concerning steroid treatment in septic shock. ‘Physiological’ doses of steroids have been shown to reduce time to shock reversal and may even be able to decrease mortality [1–3]. Assuming that forthcoming studies will confirm these results, steroid treatment will go through a revival [4]. The term: ‘relative adrenal insufficiency syndrome’ has already become established and — as mortality from severe sepsis is still more than 40% despite advances in critical care — expectations for therapeutic consequences are high.


Septic Shock Cortisol Level Intensive Care Unit Patient Adrenal Cortex Adrenal Insufficiency 
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© Springer Science+Business Media New York 2002

Authors and Affiliations

  • J. J. M. Ligtenberg
  • J. G. Zijlstra

There are no affiliations available

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