Acute Liver Failure in the ICU

  • E. Sizer
  • J. Wendon
  • W. Bernal
Conference paper

Abstract

Acute liver failure is a rare clinical syndrome resulting from severe hepatocyte injury, usually in the absence of pre-existing chronic liver disease. It is characterized by the onset of encephalopathy following the liver injury; jaundice is present in most patients but, in cases of hyperacute liver failure, encephalopathy may precede clinical jaundice. The prognosis in acute liver failure is variable, with mortality ranging from 10–90% without transplantation. The important factors determining outcome are principally: underlying etiology, age of the patient and time course over which the syndrome develops [1].

Keywords

Ischemia Lactate Aspirin Glutamine Neurol 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • E. Sizer
  • J. Wendon
  • W. Bernal

There are no affiliations available

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