A Tapered Fluidized Bed as a Bioreactor
Bioreactor systems utilizing fluidized bed techniques to contact immobilized biological fractions with liquid streams have recently been under development [e.g., (1,2)]. Such technology offers several advantages over fixed-bed systems including: (a) utilization of small particulates with high specific surface area, thus allowing greater specific reaction rates; and (b) use of particulates in a state which allows easy replacement of the active fractions even during operation -- for example, a periodic partial replenishment of the fluidized bed to maintain high reactivity.
KeywordsVoid Fraction Total Pressure Drop Entry Cross Section Void Fraction Profile Chemical Technology Division
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