Abstract
Bioreactor systems utilizing fluidized bed techniques to contact immobilized biological fractions with liquid streams have recently been under development [e.g., (1,2)]. Such technology offers several advantages over fixed-bed systems including: (a) utilization of small particulates with high specific surface area, thus allowing greater specific reaction rates; and (b) use of particulates in a state which allows easy replacement of the active fractions even during operation -- for example, a periodic partial replenishment of the fluidized bed to maintain high reactivity.
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References
CHARLES, M., COUGHLIN, R.W., ALLEN, B.R., PARUCHURI, E.K. & HASSELBERGER, F.X. In “Immobilized Biochemicals and Affinity Chromatography” (Ed. R.B. Dunlap) Plenum Press, New York, 1974. p. 213.
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© 1978 Springer Science+Business Media New York
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Scott, C.D., Hancher, C.W., Shumate, S.E. (1978). A Tapered Fluidized Bed as a Bioreactor. In: Pye, E.K., Weetall, H.H. (eds) Enzyme Engineering. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-5163-5_29
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DOI: https://doi.org/10.1007/978-1-4757-5163-5_29
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