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A Study of the Cellular and Molecular Mediators of the Adjuvant Action of a Nontoxic Monophosphoryl Lipid A

  • Chapter
Endotoxin

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 256))

Abstract

With the current resurgence of efforts to improve and expand human vaccines, attention is again being focused on the development of safe and effective adjuvants (17). In particular, the utilization of synthetic antigenic determinants or ligands of low molecular weight, which are inherently weak antigenically, necessitates the use of adjuvant carriers for optimum efficiency.

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Author information

Authors and Affiliations

  1. Department of Microbiology/Immunology, School of Medicine, University of Minnesota, Duluth, 55812, USA

    A. G. Johnson & M. A. Tomai

Authors
  1. A. G. Johnson
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  2. M. A. Tomai
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Editor information

Editors and Affiliations

  1. The University of South Florida, Tampa, Florida, USA

    Herman Friedman  & T. W. Klein  & 

  2. Jichi Medical School, Tochigi-Ken, Japan

    Masayasu Nakano

  3. University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Alois Nowotny

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© 1990 Springer Science+Business Media New York

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Johnson, A.G., Tomai, M.A. (1990). A Study of the Cellular and Molecular Mediators of the Adjuvant Action of a Nontoxic Monophosphoryl Lipid A. In: Friedman, H., Klein, T.W., Nakano, M., Nowotny, A. (eds) Endotoxin. Advances in Experimental Medicine and Biology, vol 256. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-5140-6_51

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  • DOI: https://doi.org/10.1007/978-1-4757-5140-6_51

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-5142-0

  • Online ISBN: 978-1-4757-5140-6

  • eBook Packages: Springer Book Archive

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