Tubulin and the Complexity of Life

  • Giovanni Santangelo
  • Giampaolo Magagnini


The tubulins are fascinating examples of biological complexity. These “brick proteins” polymerising, build microtubules. Microtubules in turn arrange themselves to form complex cellular structures like cilia, flagella, mitotic and meiotic spindles and others. Due to the huge number of tubulin structures and the interactions that these structures establish each other and with the other cellular components, an astonishing degree of complexity has been attained. All these structures complement one another perfectly to form the highly efficient and coordinated engines at work in eukaryotic cells. Such structural complexity can not be understood by reductionist approaches such as the simple analysis of DNA sequences codifying for tubulins.


Basal Body Mitotic Spindle Pigment Granule Biological Complexity Meiotic Spindle 
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Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Giovanni Santangelo
    • 1
  • Giampaolo Magagnini
    • 1
  1. 1.Dipartimento di etologiaecologia ed evoluzionePisaItaly

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