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Brain Laterality as a Source of Individual Differences in Behavior: Animal Models of Depression and Substance Abuse

  • Jeffrey N. Carlson
  • Isabelle M. Maisonneuve
  • Stanley D. Glick
Part of the Neurobiological Foundation of Aberrant Behaviors book series (NFAB, volume 1)

Abstract

Functional and anatomical laterality of the human brain has been studied since the early neurologist Broca reported that lesions of the left cerebral hemisphere resulted in language disorders. His findings suggested a specialized role for this hemisphere in controlling speech (Broca, 1861). Since these early reports, numerous differences between the left and right hemispheres of the human brain have been reported. Many hemispheric asymmetries have been shown to involve dominance where one hemisphere plays a greater role in control of a specific behavior (Corballis, 1991; Hellige, 1993). It has been shown, for example, that while the human left hemisphere is specialized for the processing of language, the right hemisphere has a dominant role for the processing of musical, visuospatial and emotional information (Springer and Deutsch, 1981). Lateralization of brain function often indicates that the two hemispheres are differentially proficient in controlling various behavioral activities. Differential degrees of brain lateralization appear to occur within the population. Variation in human functional brain asymmetry is associated with differences in handedness (Annett, 1985; Bryden, 1982), cognitive ability (O’Boyle and Hellige, 1989), emotional function (Davidson, 1992) and psychopathology (Flor Henry, 1986).

Keywords

Nucleus Accumbens Medial Prefrontal Cortex Inescapable Shock Rotational Behavior Ethanol Drinking 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer Science+Business Media New York 2000

Authors and Affiliations

  • Jeffrey N. Carlson
  • Isabelle M. Maisonneuve
  • Stanley D. Glick

There are no affiliations available

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