Polymersomes: A New Platform for Drug Targeting

  • Dennis E. Discher
  • Peter Photos
  • Fariyal Ahmed
  • Ranganath Parthasrathy
  • Frank S. Bates


Liposomes were first described in literature more than 30 years ago by Bangham (1). They have since been used widely in many fundamental studies of amphiphilic systems as well as in applications to extend and control the delivery of a broad variety of drugs (Fig. 1A). Thousands of publications, reviews, and monographs (e.g., (2)) now exist on liposomes. A handful of the documents have expressed ideas that emerge as the clearest backdrop for outlining the motivation, formation, properties, and compatibility of novel polymer-based vesicle platforms called “polymersomes” (3) (Fig. 1B).


Diblock Copolymer Giant Vesicle Copolymer Membrane Biomedical Aspect Stealth Liposome 


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Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Dennis E. Discher
    • 1
    • 2
  • Peter Photos
    • 1
    • 2
  • Fariyal Ahmed
    • 1
    • 2
  • Ranganath Parthasrathy
    • 1
    • 2
  • Frank S. Bates
    • 1
    • 2
  1. 1.Department of Chemical and Biomolecular Engineering, Departments of Bioengineering and Mechanical Engineering and Applied Mechanics, Institute for Medicine and EngineeringUniversity of PennsylvaniaPhiladelphiaUSA
  2. 2.Department of Chemical Engineering and Material ScienceUniversity of MinnesotaMinneapolisUSA

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