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Targeting Drugs into the Central Nervous System

  • Laszlo Prokai
Chapter

Abstract

Drugs face a formidable obstacle in reaching the central nervous systems (CNS) due to the existence and specific properties of the blood-brain barrier (BBB) that is a vital element in the regulation of the internal environment of the brain and the spinal cord. This chapter summarizes the principles and perspective of strategies that offer invasive and non-invasive approaches to overcome this major hurdle to the pharmacotherapy of the CNS.

Keywords

Passive Transport Brain Capillary Endothelial Cell Transport Vector Therapeutic Peptide Chimeric Peptide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2002

Authors and Affiliations

  • Laszlo Prokai
    • 1
  1. 1.Center for Drug Discovery and Department of Pharmaceutics, College of Pharmacy, and the McKnight Brain InstituteUniversity of FloridaGainesvilleUSA

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