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Biochemistry of Halogenated Neuroactive Amines

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Biochemistry of Halogenated Organic Compounds

Part of the book series: Biochemistry of the Elements ((BOTE,volume 9A+B))

Abstract

Included for discussion in this chapter will be halogenated analogues of amine neurotransmitters, several of which analogues function as receptor agonists, and halogenated amines that can affect neuronal function in other, less direct ways. The medicinal and pharmacological importance of both peripheral and central nervous system (CNS)-acting analogues will be reviewed. Of obvious importance are compounds that can modulate CNS functions, either to the benefit or detriment of the subject. Accordingly, the role of halogenated analogues in the development of psychotherapeutic and psychotomimetic drugs will be discussed. Analogues that have peripheral cardiovascular action also will receive special attention.

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  1. National Institutes of Health, Bethesda, Maryland, USA

    Kenneth L. Kirk

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Kirk, K.L. (1991). Biochemistry of Halogenated Neuroactive Amines. In: Biochemistry of Halogenated Organic Compounds. Biochemistry of the Elements, vol 9A+B. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-4605-1_8

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  • DOI: https://doi.org/10.1007/978-1-4757-4605-1_8

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