In recent years the use of the oral contraceptive preparations has provoked a considerable amount of discussion in the medical literature along with a vigorous reaction in the lay Press. Various side effects have been described and these have been in the main attributed to the oestrogen content of these preparations and, in particular, an increase in the incidence of venous and arterial thromboembolism in women taking oral contraceptives. (Inman, Vessey, Westerholm and Engelund, 1970; A Statement by the Committee on Safety of Drugs, 1970.) As a result of these findings the low oestrogen dosage is now being used as theincidence of serious thromboembolic phenomena is thereby significantly reduced. In addition to occlusive vascular lesions, there are numerous other complications, which in many instances require withdrawal of the drug, (Grant, 1968) and mood changes (Grant and Pryse-Davies, 1968) being two of the commoner troublesome features.
KeywordsOral Contraceptive Migraine Attack Migrainous Patient Normal Menstrual Cycle Arterial Thromboembolism
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