Molecular and Cellular Basis of Contraction and Relaxation
The ability of the heart to meet the changing demands of the circulation involves three fundamentally different mechanisms. The work of the heart can be regulated by changes in its ability to empty and fill (organ physiology), to utilize chemical energy for the performance of mechanical and osmotic work (cell biochemistry), and to replace its constituent parts (gene expression). Each of these control mechanisms operates over a different time course.
KeywordsSarcoplasmic Reticulum Thin Filament Cellular Basis Thick Filament Sodium Pump
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